When you buy through links on our site , we may clear an affiliate commission . Here ’s how it works .
A new blood test that covert for colorectal cancer has just been approved by the Food and Drug Administration ( FDA ) .
The blood sample take for the new test , called Shield , can be receive at a doctor ’s appointment or through a commercial-grade lab . The Bob Hope is that the test could boost the number of masses who get sieve for colorectal cancer , thesecond - leading cause of cancer - colligate deathsin the U.S.
A new blood-based test for colorectal cancer is designed to screen for cancer-related DNA fragments in the body.
Shield is not see an alternative to colonoscopy for diagnose the disease . Rather , it ’s a less - invading mode to droop if someone likely has cancer so they can then be triaged for further examination . The new test has been sanction for adult ages 45 and up with an average risk of infection of colorectal cancer .
The five - year survival rate for colorectal cancer is very high — over 90 % — when it ’s caught in its early stages , but that natural selection declines in modern stages . mock up studies intimate that , if gaps in colorectal cancer screening were closed , around 70%of related deaths could be avoided .
concern : Gut bacterium linked to colorectal Cancer the Crab in untried people
late datum suggest thatupwards of 1 in 3 eligible adultsare not up - to - day of the month on their recommend colorectal Cancer the Crab viewing .
" The dogged gap in colorectal cancer cover rate shows that the existing screening options do not appeal to gazillion of people,“Dr . Daniel Chung , a gastroenterologist at Massachusetts General Hospital and a prof of medicine at Harvard Medical School , said in a statementfrom Shield ’s Lord , Guardant Health . The Shield test offers a " compelling new answer to shut down this spread , " he argued .
Shield works by screening the blood line for bits of DNA shed by Crab mobile phone and polyps , which are tissue paper growths in the El Salvadoran colon that can be precancerous . In the results of a trial published in theThe New England Journal of Medicine , the test was 83 % sore for colorectal cancer , meaning it correctly identified the cancer most of the time . It missed 17 % of colorectal cancer showcase .
In a freestanding trial , 10 % of people with no colorectal cancer got a false positive — so the run is n’t perfect , but it is like to screening tests that involve taking a stool sample .
The clinical test also find that Shield is n’t bang-up at detecting advanced precancerous polypus ; it spotted them in only 13 % of instance . That ’s why the trial would n’t be an appropriate replacement for more - invasive tests , such ascolonoscopies , which involve using a long , lean scope to examine the entire colon and are very upright at finding polyp .
Thus , a soul who test positive for cancer on the Shield test would call for a follow - up colonoscopy to confirm the diagnosis and locate the tumor .
Current guidelines recommendthat masses bulge out getting screen for colorectal cancer at years 45 , if they ’re at average peril of the disease . There are several choice for screening : The stool - free-base tests should be used annually or every one to three twelvemonth , bet on the specific run used , while colonoscopies are recommend every 10 year . A exam that ’s used less frequently in the U.S. , called pliable sigmoidoscopy , is recommended every five years .
Shield would be given every three year , NBC News reported .
— The 10 deadliest genus Cancer , and why there ’s no cure
— ' I ’ve never seen anything like this ' : Scientists hijack cancer genes to rick neoplasm against themselves
— notice cancer in hour possible with just a drop of dry parentage and new test , field jot
Now that it ’s approved , Shield is the 2d rake - based colorectal cancer test to be approved by the FDA . However , the first , Epi proColon , isn’t covered by Medicaredue to concerns over its accuracy and welfare . It ’s anticipate that both Medicare and secret insurance will cover Shield , whose list price has yet to be declare .
The newfangled test is a " welcome development,“Dr . Arvind Dasari , an associate professor in the Department of Gastrointestinal and Medical Oncology at the University of Texas MD Anderson Cancer Center , severalise NBC News .
However , " we ’ll have to hold off and see what the impact will be in terms of improving masking and shrink the relative incidence of death rate , " he say .
Ever wonder whysome people build sinew more easily than othersorwhy lentigo come out in the Dominicus ? Send us your interrogation about how the human body works tocommunity@livescience.comwith the subject line " Health Desk Q , " and you may see your question answered on the website !
